In August 1852, after returning to Boston from her first voyage, it was advertised that for eight consecutive days she had averaged 293 miles and on one day had logged 346 miles.

On her first passage to San Francisco, the Monsoon reached port Jan. 6, 1853, in 130 days from Boston. Captain Winsor reported having had succession of light winds throughout and being four days off the Heads in thick fog. She went to Singapore in 50 days from the Golden Gate; thence 35 days to Calcutta and 102 days from there to New Bedford. Captain Baker assumed command and leaving Boston, Jan 4, 1854, was 19 days to the line; 60 days to Cape Horn, crossing the equator on the 97th day; then had the very fast run of 16 days to sighting land but was blown off and did not pass through the Golden Gate until May 4th, seven days later, in 120 days from Boston. Went to Callao in 48 days; thence 85 days to Baltimore. On her last Cape Horn passage to San Francisco she left New York, Feb. 27, 1855; was 30 days to the line; thence all light winds to destination except for the 30 days rounding Cape Horn; reached destination Aug. 2nd, 154 days out. Completing the voyage she crossed to China and reached New York, Apr. 7, 1856, in 109 days from Foo Chow and 94 days from Anjer. Sailed from New York, July 26, 1856, and arrived in Hudson's Bay, Nov. 11th. It was reported that she hove to off Sydney and was driven into a cove where she lost her anchors and was obliged to substitute a canon. From Melbourne she went to Singapore, Calcutta, China and home.

Under Captain Loring she left New York, Aug. 1, 1861; passed Anjer, Nov. 19th, and arrived at Hong Kong, Dec. 31st. Went to Bangkok and Singapore, sailing from the latter port, Mar. 21, 1862; passed Anjer, Mar. 30th; the Cape; May 11th; had light winds to line, June 9th, and arrived at New York, July 6th. Loaded for Australia, arriving at Newcastle, Jan 19, 1863; thence to Shanghai and Manila. On Dec. 30, 1864, she arrived at San Francisco, Feb. 9, 1865; was 19 days to line; 40 days thence to Cape Horn; crossed the equator May 17th and was thence 21 days to New York, arriving June 7th, in a passage of 117 days.

In 1865 the Monsoon, which up to that time had been owned by George Hussy, was reported sold for $23,000 and the register of 1866 gives her owners as Ruger Brothers of Geestmünde, and Captain Closson as her commander. [American Clipper Ships" 1833 - 1858 by Octavius T. Howe, M.D. and Fredrick C. Matthews Volume II, Salem, Mass., Marine Research Society 1927]